Publikationen: Dr. Falko Lange

Lange F, Hörnschemeyer J, Kirschstein T. Glutamatergic Mechanisms in Glioblastoma and Tumor-Associated Epilepsy. Cells. 2021 May 17;10(5):1226.

Henze L, Walter U, Murua Escobar H, Junghanss C, Jaster R, Köhling R, Lange F, Salehzadeh-Yazdi A, Wolkenhauer O, Hamed M, Barrantes I, Palmer D, Möller S, Kowald A, Heussen N, Fuellen G. Towards biomarkers for outcomes after pancreatic ductal adenocarcinoma and ischaemic stroke, with focus on (co)-morbidity and ageing/cellular senescence (SASKit): protocol for a prospective cohort study. BMJ Open. 2020 Dec 17;10(12):e039560.

Lange F, Hartung J, Liebelt C, Boisserée J, Resch T, Porath K, Hörnschemeyer J, Reichart G, Sellmann T, Neubert V, Kriesen S, Hildebrandt G, Schültke E, Köhling R, Kirschstein T. Perampanel add-on to standard radiochemotherapy in vivo promotes neuroprotection in a rodent F98 glioma model. Front Neurosci. 2020 Nov 30;14:598266.

Madadi A, Wolfart J, Lange F, Brehme H, Linnebacher M, Bräuer AU, Büttner A, Freiman T, Henker C, Einsle A, Rackow S, Köhling R, Kirschstein T, Müller S. Correlation between Kir4.1 expression and barium-sensitive currents in rat and human glioma cell lines. Neurosci Lett. 2021 Jan 10;741:135481.

Mayer J, Kirschstein T, Resch T, Porath K, Krause BJ, Köhling R, Lange F. Perampanel attenuates epileptiform phenotype in C6 glioma. Neurosci Lett. 2019 Nov 14:134629.

Lange F, Weßlau K, Porath K, Hörnschemeyer J, Bergner C, Krause BJ, Mullins CS, Linnebacher M, Köhling R, Kirschstein T. AMPA receptor antagonist perampanel affects glioblastoma cell growth and glutamate release in vitro. PLoS One. 2019 Feb 4;14(2):e0211644.

Reichart G, Mayer J, Zehm C, Kirschstein T, Tokay T, Lange F, Baltrusch S, Tiedge M, Fuellen G, Ibrahim S, Köhling R. Mitochondrial complex IV mutation increases ROS production and reduces lifespan in aged mice. Acta Physiol (Oxf). 2018 Oct 30:e13214.

Gock M, Mullins C, Bergner C, Prall F, Ramer R, Goeder A, Krämer OH, Lange F, Krause BJ, Klar E, Linnebacher M. Establishment, functional and genetic characterization of three novel patient-derived rectal cancer cell lines. World J Gastroenterol 2018 November 21; 24(43): 4880-4892

Wallbaum P, Rohde S, Borufka L, Lange F, Hohn A, Bergner C, Schwarzenböck SM, Krause BJ, Jaster R. Antifibrogenic effects of vitamin D derivatives on rat pancreatic stellate cells. World J Gastroenterol. 2018 Jan 14;24(2):170-178.

Rohde S, Lindner T, Polei S, Stenzel J, Borufka L, Achilles S, Hartmann E, Lange F, Maletzki C, Linnebacher M, Glass Ä, Schwarzenböck SM, Kurth J, Hohn A, Vollmar B, Krause BJ, Jaster R. Application of in vivo imaging techniques to monitor therapeutic efficiency of PLX4720 in an experimental model of microsatellite instable colorectal cancer. Oncotarget. 2017 Jul 15;8(41):69756-69767.

Smita S, Lange F, Wolkenhauer O, Köhling R. Deciphering hallmark processes of aging from interaction networks. Biochim Biophys Acta. 2016 Jul 22. pii: S0304-4165(16)30264-1.

Hirose M, Schilf P, Lange F, Mayer J, Reichart G, Maity P, Jöhren O, Schwaninger M, Scharffetter-Kochanek K, Sina C, Sadik CD, Köhling R, Miroux B, Ibrahim SM. Uncoupling protein 2 protects mice from aging. Mitochondrion. 2016 Jun 27. pii: S1567-7249(16)30078-2.

Mayer J, Reichart G, Tokay T, Lange F, Baltrusch S, Junghanss C, Wolkenhauer O, Jaster R, Kunz M, Tiedge M, Ibrahim SM, Fuellen G, Köhling R. Reduced Adolescent-Age Spatial Learning Ability Associated with Elevated Juvenile-Age Superoxide Levels in Complex I Mouse Mutants. PLoS One. 2015 Apr 8;10(4):e0123863.

Lange F*, Franz B*, Maletzki C, Linnebacher M, Hühns M, Jaster R. Biological and molecular effects of small molecule kinase inhibitors on low-passage human colorectal cancer cell lines. BioMed Research International. Biomed Res Int. 2014; 2014:568693.

Müller S, Krüger B, Lange F, Bock CN, Nizze H, Glass A, Ibrahim SM, Jaster R. The mtDNA nt7778 G/T Polymorphism Augments Formation of Lymphocytic Foci but Does Not Aggravate Cerulein-Induced Acute Pancreatitis in Mice. PLoS One. 2014; 9(7):e102266.

Elsner A*, Lange F*, Fitzner B, Heuschkel M, Krause BJ, Jaster R. Distinct antifibrogenic effects of erlotinib, sunitinib and sorafenib on rat pancreatic stellate cells. World J Gastroenterol 2014; 20(24): 7914-7925.

Müller S*, Kaiser H*, Krüger B, Fitzner B, Lange F, Bock CN, Nizze H, Ibrahim SM, Fuellen G, Wolkenhauer O, Jaster R. Age-dependent effects of UCP2 deficiency on experimental acute pancreatitis in mice. PLoS One. 2014; 9(4):e94494.

Lange F*, Rateitschak K*, Kossow C, Wolkenhauer O, Jaster R. Insights into erlotinib action in pancreatic cancer cells using a combined experimental and mathematical approach. World J Gastroenterol. 2012; 18(43):6226-6234.

Rateitschak K, Winter F, Lange F, Jaster R, Wolkenhauer O. Parameter Identifiability and Sensitivity Analysis Predict Targets for Enhancement of STAT1 Activity in Pancreatic Cancer and Stellate Cells. PLoS Comp Biol. 2012; 8(12):e1002815.

Vera J, Rateitschak K, Lange F, Kossow C, Wolkenhauer O, Jaster R. Systems biology of JAK-STAT signalling in human malignancies. Prog Biophys Mol Biol. 2011; 106(2):426-34.

Lange F*, Rateitschak K*, Fitzner B, Pöhland R, Wolkenhauer O, Jaster R. Studies on mechanisms of interferon-gamma action in pancreatic cancer using a data-driven and model-based approach. Mol Cancer. 2011; 10(1):13.

Rateitschak K, Karger A, Fitzner B, Lange F, Wolkenhauer O, Jaster R. Mathematical modelling of interferon-gamma signalling in pancreatic stellate cells reflects and predicts the dynamics of STAT1 pathway activity. Cell Signal. 2010; 22(1):97-105.

Lange F, Brandt B, Tiedge M, Jonas L, Jeschke U, Pöhland R, Walzel H. Galectin-1 induced activation of the mitochondrial apoptotic pathway: evidence for a connection between death-receptor and mitochondrial pathways in human Jurkat T lymphocytes. Histochem Cell Biol. 2009; 132(2):211-23.

(*gleichberechtigte Autorschaft)